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Treatment-experienced people news

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Treatment-experienced people
Once-daily darunavir/ritonavir may be an option for some treatment-experienced patients

A once-daily dose of ritonavir-boosted darunavir (Prezista) may be an option for some treatment-experienced patients, according to a small study published in the October 1st

Published
30 October 2008
By
Michael Carter
Resistance
Etravirine (TMC125, Intelence) granted accelerated approval in US

The second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) etravirine (formerly TMC125) was granted accelerated approval by the US Food and Drug Administration (FDA) last Friday, January

Published
21 January 2008
By
Edwin J. Bernard
Treatment-experienced people
Triple-class failure emerges slowly in UK patients

Evidence from a large cohort of HIV-positive patients in the UK suggests that extensive virological failure of the three main classes of antiretroviral drugs emerges

Published
07 December 2007
By
Michael Carter
Resistance
Start treatment when CD4 cell count is 350, say revised US guidelines

The US Department of Health and Human Services (DHHS) has issued revised adult antiretroviral treatment guidelines. The US guidelines, like the revised European guidelines issued

Published
05 December 2007
By
Michael Carter
Treatment-experienced people
Bevirimat 300mg oral solution dose does well in study

A 300mg once-daily oral solution dose of the maturation inhibitor, bevirimat (PA-457), has a potent anti-HIV effect and is well tolerated, according to the results

Published
26 October 2007
By
Michael Carter
Changing treatment
Undetectable viral load is goal for all, together with earlier treatment, say new European treatment guidelines

All HIV-positive people in Europe should be encouraged to start antiretroviral therapy if they have a CD4 cell count below 350, say new European HIV

Published
25 October 2007
By
Gus Cairns
Treatment-experienced people
Raltegravir receives accelerated approval from the FDA

The US Food and Drug Administration (FDA) has granted accelerated approval Merck’s integrase inhibitor, raltegravir (Isentress). Approval of the drug was based upon safety and

Published
15 October 2007
By
Michael Carter
Treatment-experienced people
Most patients on incompletely suppressive therapy maintain CD4 counts and stable viral loads

Two-thirds of patients on anti-HIV therapy that failed to reduce their viral loads to undetectable levels (‘incompletely suppressive therapy’ or ISR) maintained or increased their

Published
04 October 2007
By
Gus Cairns
Side-effects
Roche abandon Biojector 2000 for T-20 administration

Drug company Roche has withdrawn its application to US regulatory authorities for approval of a needle-free way of administering their fusion inhibitor T-20 (enfuvirtide, Fuzeon). T-20

Published
04 October 2007
By
Michael Carter
Treatment-experienced people
ICAAC: 48-week results show maraviroc still potent in highly treatment-experienced

Forty-eight week results from the MOTIVATE 1 study of maraviroc in highly treatment-experienced patients show viral suppression is still being maintained in the majority of

Published
20 September 2007
By
Keith Alcorn
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